Gastrointestinal Cancer News

Herbert J. Zeh, III, has been chosen as the next chair of the department of surgery at UT Southwestern.

Adjuvant chemotherapy appeared associated with improved OS among patients with rectal cancer who achieved pathological complete response after neoadjuvant chemotherapy and resection, according to two studies published in JAMA Oncology.

The American Society for Gastrointestinal Endoscopy has released new guidelines on the use of endoscopic eradication therapy in patients with Barrett’s esophagus-related dysplasia and intramucosal cancer.

Transanal endoscopic total mesorectal excision showed positive results in a phase 2 trial of patients with rectal cancer, according to research published in Diseases of the Colon & Rectum.

Probe-based confocal laser endomicroscopy with Mauna Kea Technologies’ Cellvizio platform was superior for detecting Barrett’s esophagus compared with the standard Seattle protocol, according to new research presented at the Society of American Gastrointestinal and Endoscopic Surgeons 2018 Annual Meeting and World Congress of Endoscopic Surgery.

CHICAGO — Prototype sequencing assays evaluated in the Circulating Cell-free Genome Atlas study may contribute to the development of a highly specific blood test for early cancer detection, according to training set findings presented at American Association for Cancer Research Annual Meeting.

Calcium channel blockers, specifically the short-acting form, appeared associated with increased risk for pancreatic cancer among postmenopausal women, according to a study presented at American Association for Cancer Research Annual Meeting.

The addition of the highly selective IDO1 inhibitor epacadostat to the PD-L1 inhibitor durvalumab appeared safe for patients with advanced solid tumors, according to results of the ECHO-203 trial presented at American Association for Cancer Research Annual Meeting.

CHICAGO — Taselisib demonstrated preliminary clinical activity and exhibited an acceptable safety profile as monotherapy for patients with PIK3CA-mutated locally advanced or metastatic solid tumors, according to results of a basket study presented at American Association for Cancer Research Annual Meeting.

CHICAGO — Children with nonchromosomal birth defects such as congenital heart disease and central nervous system defects demonstrated significantly higher risk for certain childhood cancers, according to study results presented at American Association for Cancer Research Annual Meeting.