Gastrointestinal Cancer News

The FDA granted breakthrough therapy designation to the combination of encorafenib, binimetinib and cetuximab for the treatment of patients with BRAF V600E-mutant metastatic colorectal cancer following the failure of one or two prior lines of therapy, according to the manufacturer.

Health care centers that used an electronic health care record-embedded tool to help identify patients eligible for colorectal cancer screening improved their screening rates using mailed fecal immunochemical tests, according to research published in JAMA Internal Medicine.

Patients with Barrett high-grade dysplasia and esophageal adenocarcinoma who had HPV-positive tumors had improved DFS and OS compared with those with HPV-negative tumors, according to results from a retrospective case-control study.

Higher levels of branched-chain amino acids in the blood correlated with a higher risk for pancreatic cancer, according to research published in Gastroenterology.

Patients with complicated diverticulitis are six times more likely to develop colorectal cancer than patients with uncomplicated diverticulitis, according to a systematic review and meta-analysis published in Clinical Gastroenterology and Hepatology.

Sixty-five percent of adult survivors of childhood cancer experienced financial hardships related to their earlier diagnosis, according to findings from a cross-sectional study.

The presence of occult blood in feces is associated with increased risk of death from a number of causes in addition to colorectal cancer, according to research published in Gut.

A machine learning algorithm used medical records to accurately predict 30-day mortality among patients starting chemotherapy, according to results of a retrospective cohort study published in JAMA Network Open.

Two brands of fecal immunochemical tests were equally accurate in detecting advanced neoplasia, according to data from a head-to-head trial published in Gastroenterology.

Black patients with esophageal cancer have shorter survival times compared with other patients, which could be due to the underuse of surgery in the population, according to research published in Clinical Gastroenterology and Hepatology.