HemOnc Today Current Issue

The following articles appeared in the print edition of HemOnc Today.

Table of Contents

• Despite increased scrutiny, bias remains ‘concerning’ component of cancer research
• Advisory committee members appointed
• Best practice DVT approach may save health systems $4 million annually
• BRAF mutation increased mortality for papillary thyroid cancer
• Breast density modulation, AEs predicted response to therapy
• FDA proposes new tanning bed requirements, including skin cancer warnings
• Novel oral anticoagulants more cost effective than warfarin
• Online medical professionalism statement targets social media use
• Professor receives 2013 Pinedo Prize
• Radiation increased risk for cardiovascular events later in life
• Zibotentan/docetaxel failed to improve OS in metastatic castration-resistant prostate cancer
• Advisory committee votes against tivozanib for RCC
• FDA approves 2-D mammography software
• FDA approves Tafinlar, Mekinist as treatment for metastatic melanoma
• FDA approves Xofigo for metastatic prostate cancer
• FDA grants ‘breakthrough’ status for daratumumab
• Thyroid tissue uptake represents confounding variable in detection of regional metastasis
• Few textbook answers when making decisions amid significant uncertainty William Wood, MD
• 21-day R-CHOP regimen remains standard in diffuse B-cell lymphomas
• Biomarker screening identified early-stage renal cell carcinomas
• IMRT yielded encouraging local control in certain pediatric gliomas
• PLCO model more accurate in predicting cancer than NSLT criteria
• Gemcitabine/paclitaxel improved PFS, OS in metastatic breast cancer
• Suicide rates may be higher in stem cell transplant recipients
• Surgical treatments may reduce ovarian cancer recurrence
• Addition of lapatinib to paclitaxel extended survival in women with HER-2 breast cancer
• Alzheimer’s disease risk significantly reduced among older NMSC patients
• Annual screening may benefit younger women with dense breasts
• Arsenic trioxide, stem cell harvest sequence shows promise in APL
• Aspirin use significantly lowered melanoma risk in postmenopausal Caucasians
• Bendamustine plus rituximab shows promise in relapsed, refractory DLBCL
• Better outcomes anticipated when SCC invade smaller nerves
• Blood clots may increase white matter hyperintensities after menopause
• BRCA status predicted risk-reducing salpingo-oophorectomy
• Colorectal adenomas more common among men, older patients
• DNA test may be effective biomarker in breast cancer treatment
• False-positive mammography results may have long-term psychological consequences
• Father’s obesity may increase newborn’s risk for cancer later in life
• Gadoxetic acid-enhanced magnetic resonance improved diagnosis of HCC in small nodules
• Guidelines recommend low-dose CT scans for those at high risk for lung cancer
• IFRT offers viable alternative to WBRT
• Low-dose CT screening could avert 12,000 lung cancer deaths annually
• Low-dose hydroxyurea shows promise in sickle cell disease
• Melanoma simulation helped students improve performance
• Meta-analysis indicates potential link between IBD, VTE
• New-onset diabetes highly prevalent among patients with pancreatic cancer
• No melanomas developed at sites of incompletely excised histologically dysplastic nevi
• Plaque radiotherapy effective in managing iris melanoma
• Potentially inappropriate colonoscopies common among older patients
• Pregnancy did not affect maternal prognosis of breast cancer
• Recurrence risk factors important to consider in H. pylori eradication
• Reflectance confocal microscopy confirmed histopathologic diagnoses of balanitis, carcinoma
• Relative risk for invasive melanoma greater among RA patients treated with anti-TNFs
• Retransplantation plus novel chemotherapy produced synergistic effect
• Review highlights ‘imbalances, distinctions’ within oncology trials
• Stool DNA testing detected colorectal neoplasia in IBD patients
• Study identifies adverse events and risk factors after knee arthroscopy
• Study supports SLNB for all primary Merkel cell carcinoma
• Urothelial cancer clinical trials tended to be small, identical between institutions
• Duloxetine reduced pain from chemotherapy-induced peripheral neuropathy
• Cardiovascular fitness in middle-aged men reduced cancer risk, mortality
• Statin, aspirin use linked to decreased mortality in uterine cancer
• Adult endometrial cancer risk possibly linked to childhood BMI, height
• FUSE colonoscopy produced better adenoma detection, miss rates vs. TFV
• Glioblastoma vaccine offered better survival rates than standard care
• H. pylori infection less common among patients with Barrett's esophagus, erosive esophagitis
• HBV may increase risk for non-Hodgkin lymphoma
• HPV, p16 expression associated with significant improvement in response, OS in recurrent, metastatic SCCHN
• IMRT showed fewer adverse effects than standard radiotherapy
• Nintedanib associated with comparable effectiveness, fewer adverse events than sunitinib in RCC
• PD-L1 targeted antibody induced tumor shrinkage in several cancer types
• Select patients with colorectal cancer, UC benefit from partial colectomy
• Smaller radiation dose reduced dry mouth symptoms in certain cancers
• Spouses of patients with HPV-associated oropharyngeal cancer not at increased risk
• Thoracic endografts may allow safe resection of tumors in aorta
• Nivolumab induced long-lasting response in stage IV melanoma
• Novel ALK TKI shows promise in NSCLC