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Cell Therapy News
CAR-T effective for younger patients with leukemia, regardless of socioeconomic status
Socioeconomic status had no impact on complete remission rates or overall survival among younger patients who received chimeric antigen receptor T-cell therapy for B-cell acute lymphoblastic leukemia, study results showed.
Cell-based therapy fails to significantly improve outcomes in metastatic renal cell carcinoma
The addition of a cell-based immune primer to sunitinib exhibited activity among patients with metastatic renal cell carcinoma, according to randomized phase 2 study results.
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CAR-T regimen ‘should be new standard’ for high-risk B-cell acute lymphoblastic leukemia
Dual administration of CD19- and CD22-directed chimeric antigen receptor T cells conferred a 99% complete remission rate in younger patients with relapsed or high-risk B-cell acute lymphoblastic leukemia, phase 2 study results showed.
Revaccination guidance after cell therapy established for some, ‘evolving’ for others
Guidelines on revaccination after cell therapy are clear for some patients but lack evidence-based consensus for others, according to an expert in infectious disease who spoke at NCCN 2022 Annual Congress: Hematologic Malignancies.
FDA grants fast track designation to CAR monocyte therapy for peripheral T-cell lymphoma
The FDA granted fast track designation to MT-101, an investigational chimeric antigen receptor monocyte, for the treatment of relapsed or refractory peripheral T-cell lymphoma.
Bispecific CAR-T induces response in blood cancers
Three-quarters of patients with advanced B-cell malignancies who received an investigational chimeric antigen receptor T-cell therapy achieved complete response, according to the agent’s manufacturer.
Carl H. June, MD, to receive award for translational scientific research
Carl H. June, MD, will receive the inaugural Maria I. New International Prize for Biomedical Research.
ASH announces new executive committee members
Four individuals have been elected to American Society of Hematology’s executive committee.
‘Immunotherapy is here’ for treatment of multiple myeloma
Novel B-cell maturation antigen-directed immunotherapies are ready to take their place as the new standard for treatment of advanced multiple myeloma, according to a panel at NCCN 2022 Annual Congress: Hematologic Malignancies.
‘Multipronged effort’ needed to increase diversity in CAR-T clinical trials
Emerging evidence has shown chimeric antigen receptor T-cell therapies are highly effective regardless of a patient’s race or ethnicity.
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Headline News
A potential new paradigm for treating acute migraine: Timolol nasal spray
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Headline News
A potential new paradigm for treating acute migraine: Timolol nasal spray
November 15, 20245 min read -
Headline News
AI-enabled video of skin on face, hands may detect high blood pressure, diabetes
November 15, 20242 min read -
Headline News
‘Troubling’ data show lack of awareness about lung cancer screening
November 15, 20242 min read