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Cell Therapy News
Fourth-generation autologous CAR-T product shows efficacy for pretreated lymphoma
NEW ORLEANS — A novel chimeric antigen receptor T-cell therapy showed encouraging early efficacy among heavily pretreated patients with CD19-positive non-Hodgkin lymphoma, according to study results.
Bendamustine lymphodepletion effective, safe as part of CAR-T for advanced lymphoma
NEW ORLEANS — Bendamustine lymphodepletion resulted in significant CAR T-cell expansion among patients with relapsed or refractory non-Hodgkin lymphoma, according to study results presented at ASH Annual Meeting and Exposition.
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BLOG: CAR T cells for long-term cure in pediatric ALL
Chimeric antigen receptor T-cell therapy targeting CD19 is highly effective for inducing remission among patients with relapsed or refractory B-cell acute lymphoblastic leukemia.
Recent exposure to chemotherapy drug linked to worse outcomes among CAR-T recipients
NEW ORLEANS — Patients recently treated with bendamustine had significantly lower response rates to subsequent chimeric antigen receptor T-cell therapy for non-Hodgkin lymphoma, data presented at ASH Annual Meeting and Exposition showed.
Pediatric oncologist uses patient-centered approach to drive CAR-T innovation
Shannon L. Maude, MD, PhD, always knew she wanted to work with children — she just didn’t always know how she could best help them.
Off-the-shelf CAR T cells hold ‘huge’ promise for cancer treatment, but more data needed
Speed matters when it comes to treatment of highly aggressive cancers.
Study of CAR-T for patients with non-Hodgkin lymphoma, HIV yields 'reassuring' results
NEW ORLEANS — Chimeric antigen receptor T cells demonstrated acceptable efficacy with no additional safety concerns when administered to patients with non-Hodgkin lymphoma and HIV, retrospective study results showed.
BLOG: Organizations partner to expand access to bone marrow transplant, cell therapy
Bone marrow transplant and cellular therapies are the only known curative therapy for many patients with hematologic malignancies or other disorders of blood and immune systems.
VIDEO: New CAR-T targets show activity
NEW ORLEANS — In this video perspective, Samer Al Hadidi, MD, MS, FACP, discusses research evaluating G protein–coupled receptor as a new target for therapy in relapsed refractory multiple myeloma.
Experimental CAR-T safe, ‘highly effective’ for certain patients with T-cell malignancies
NEW ORLEANS — A novel chimeric antigen receptor T-cell therapy conferred a 78% complete response rate in patients with heavily pretreated T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma, study results showed.
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Headline News
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