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Bone Marrow Transplantation News
HSCT for beta-thalassemia improved long-term quality of life
Patients with beta-thalassemia who underwent hematopoietic stem cell transplantation experienced similar long-term quality of life as individuals in the general population, according to study results.
Cyclophosphamide plus busulfan improves survival after AML remission
Patients with acute myelogenous leukemia in first remission treated with cyclophosphamide plus busulfan experienced longer leukemia-free survival and OS than those treated with cyclophosphamide plus total body irradiation, according to results of a retrospective study.
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Cyclophosphamide plus busulfan improves survival after AML remission
Patients with acute myelogenous leukemia in first remission treated with cyclophosphamide plus busulfan experienced longer leukemia-free survival and OS than those treated with cyclophosphamide plus total body irradiation, according to results of a retrospective study.
Central line maintenance care bundle reduced infections, bacteremia
Use of a multidisciplinary central line maintenance care bundle significantly reduced central line–associated bloodstream infections and bacteremias in an ambulatory pediatric cancer patients, according to study results.
Rituximab prevented corticosteroid-requiring chronic GVHD
Rituximab prophylaxis considerably reduced corticosteroid-requiring chronic graft-vs.-host disease in patients who underwent allogeneic peripheral blood stem cell transplantation, according to results of a prospective, open-label, phase 2 study.
CMX001 reduced cytomegalovirus disease after HSCT
Patients who underwent hematopoietic stem cell transplantation were less likely to contract cytomegalovirus disease when treated with higher doses of CMX001, according to results of a randomized study.
High levels of ST2 associated with treatment resistance, death in GVHD
Improvements in risk stratification to predict treatment-resistant acute graft-versus-host disease and mortality without relapse were observed when suppression of tumorigenicity 2 levels were measured at therapy initiation and within the first month after stem cell transplantation, according to recent study findings.
High levels of ST2 associated with treatment resistance, death in GVHD
Improvements in risk stratification to predict treatment-resistant acute graft-versus-host disease and mortality without relapse were observed when suppression of tumorigenicity 2 levels were measured at therapy initiation and within the first month after stem cell transplantation, according to recent study findings.
Cell vaccination early after transplant may increase T cells in CLL
Vaccination with whole leukemia cells shortly after allogeneic hematopoietic stem cell transplantation was associated with increased long-term disease control in a cohort of patients with chronic lymphocytic leukemia, according to results of a prospective trial.
Allogeneic HSCT improved outcomes for children with relapsed ALL
Allogeneic hematopoietic stem cell transplantation considerably improved the prognosis of patients with acute lymphoblastic leukemia who demonstrated unsatisfactory reduction of minimal residual disease after induction therapy and were at intermediate risk for relapse, according to study results.
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Headline News
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