Bone Marrow Transplantation News

Last June, we launched a series of columns in HemOnc Today intended to discuss high-priority proposals that emerged from the 2014 Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium.

Patients who underwent hematopoietic stem cell transplantation had a considerably higher incidence of fractures compared with the general population, according to results of a retrospective analysis.

VIENNA — Hepatitis B virus infection reactivation was prevalent in treatment-naive patients undergoing hematopoietic stem cell transplantation, according to data presented at the 2015 International Liver Congress.

PHILADELPHIA — A new type of T cell-based immunotherapy induced response in a majority of patients with Epstein-Barr virus-associated lymphoproliferative disorder who did not respond to standard treatment, according to study results presented at the American Association for Cancer Research Annual Meeting.

Routine testing for respiratory viruses before hematopoietic cell transplantation is reasonable in symptomatic patients and transplantation should be delayed when possible, according to recent data.

 Pediatric patients with high-risk acute lymphoblastic leukemia who underwent hematopoietic stem cell transplantation with matched unrelated donors demonstrated comparable survival outcomes to those who had matched sibling donors, according to study results.

Outcomes of cytomegalovirus pneumonia after hematopoietic cell transplantation have improved modestly over the past 25 years largely due to antiviral treatment and changes in transplantation protocols rather than the use of adjunctive immunoglobulin treatment, according to recent findings.

Although the number of hematopoietic stem cell transplants performed worldwide reached 1 million in 2012, the procedure is primarily utilized by patients who reside in wealthier countries with larger donor registries, according to study results.

Longer donor leukocyte telomere length was associated with improved survival in patients with severe aplastic anemia who underwent allogeneic hematopoietic stem cell transplantation, according to study results.

Allogeneic hematopoietic stem cell transplantation was associated with significantly improved RFS in patients with acute myeloid leukemia who harbored nucleophosmin-1 gene mutations, according to study results.