Bone Marrow Transplantation News

SALT LAKE CITY — A diverse gut microbiota demonstrated a local protective effect among patients with nongastrointestinal or upper gastrointestinal acute graft-versus-host disease, according to study results presented at the BMT Tandem Meetings.

SALT LAKE CITY — The chimeric antigen receptor T-cell therapy axicabtagene ciloleucel induced significant clinical benefit with manageable adverse events among patients with refractory aggressive non-Hodgkin lymphoma, according to long-term follow-up of the pivotal ZUMA-1 clinical trial presented at the BMT Tandem Meetings.

SALT LAKE CITY — NiCord single unit expanded umbilical cord blood transplantation decreased time to neutrophil and platelet recovery, according to results of a phase 2 study presented at the BMT Tandem Meetings.

SALT LAKE CITY — Wild-type alleles found in the rs1042713 genotype of the beta-2 adrenergic receptor gene appeared to prolong time to optimal pain control and increase time on scheduled opioids among pediatric patients with mucositis following hematopoietic stem cell transplantation, according to study results presented at the BMT Tandem Meetings.

SALT LAKE CITY — Hematopoietic stem cell transplant physicians reported substantial concerns about palliative care clinicians’ knowledge about transplant, according to results of a cross-sectional, web-based survey presented at the BMT Tandem Meetings.

SALT LAKE CITY — Extracorporeal photopheresis stabilized forced expiratory volume in the first breath, or FEV1, values and prolonged survival among patients with bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation, according to results of a multisite retrospective cohort study presented at the BMT Tandem Meetings.

SALT LAKE CITY — Patients with relapsed or refractory acute lymphoblastic leukemia who achieved complete response to inotuzumab ozogamicin and directly proceeded to hematopoietic stem cell transplantation showed promising OS, according to study results presented at the BMT Tandem Meetings.

SALT LAKE CITY — Preliminary data have suggested the potential role for immune checkpoint inhibitors in the posttransplant setting among patients with relapsed/ large B-cell lymphomas, according to a presenter at the BMT Tandem Meetings.

SALT LAKE CITY — Financial and employment hardships appeared common among adults with graft-versus-host disease following hematopoietic stem cell transplant, according to study results presented at the BMT Tandem Meetings.

SALT LAKE CITY — Ruxolitinib treatment prior to allogeneic hematopoietic stem cell transplant appeared safe and aided in the prevention of cytokine release syndrome among patients with myelofibrosis, according to results of a phase 2 prospective study presented at the BMT Tandem Meetings.