Bone Marrow Transplantation News

Survival appeared comparable following a second allogeneic hematopoietic stem cell transplant or donor lymphocyte infusion among patients with acute myeloid leukemia who relapsed after first HSCT, according to results of a retrospective registry study.

A whole genome-based approach to antigen matching of patients with blood donors may represent a novel method to improve blood transfusion outcomes, according to study results published in The Lancet Haematology.

The FDA issued a warning that azithromycin should not be administered long term to prevent bronchiolitis obliterans syndrome among patients with cancers of the blood or lymph nodes who undergo a donor stem cell transplant.

Patients who underwent blood or marrow transplantation during childhood remained at greater risk for death up to 25 years later compared with the general population, according to a study published in JAMA Oncology.

The FDA approved the biosimilar filgrastim-aafi, designed to promote white blood cell recovery among individuals who have undergone treatments that can trigger neutropenia.

Researchers from the American Cancer Society identified trends in disparities and outcomes for cancer over the last few decades in an effort to highlight the need for better quality care for all individuals with cancer, according to a report published in CA: A Cancer Journal for Clinicians.

A phase 2 trial of ruxolitinib met its primary endpoint of overall response rate for the treatment of patients with steroid-refractory graft-versus-host disease, according to the agent’s manufacturer.

Longer donor leukocyte telomere length appeared associated with reduced infection-related mortality among patients with severe aplastic anemia who underwent hematopoietic stem cell transplantation, according to study results.

Click here to read the Cover Story, “GVHD management improves, but questions remain about risk stratification, prophylaxis.”

The FDA approval of ibrutinib for adults with chronic graft-versus-host disease may herald a practice-changing breakthrough in the management of this posttransplant complication.