VIDEO: Proteolysis-targeting chimeras show promising results in prostate cancer
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In this video, Alexander Chehrazi-Raffle, MD, discusses the results of a phase 1/phase 2 study into proteolysis-targeting chimeras in prostate cancer treatment, presented at ASCO Annual Meeting.
Chehrazi-Raffle, a medical oncologist at the City of Hope Duarte Cancer Center, saw “encouraging” numbers in the use of the PROTAC ARV-766 in metastatic castration-resistant prostate cancer.
“In this patient population, that is quite impressive because these are heavily pretreated patients on several lines of therapy prior to this treatment, so I think it does represent a potential novel targeted strategy that may be in the pipeline in the months to years to come,” Chehrazi-Raffle said.