March 20, 2024
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VIDEO: Notable PFS improvement from nivolumab plus ipilimumab for colorectal cancer
In this video, Afsaneh Barzi, MD, PhD, discusses the results of the CheckMate 8HW study.
The study, presented at ASCO Gastrointestinal Cancers Symposium, found that nivolumab (Opdivo, Bristol Myers Squibb) plus ipilimumab (Yervoy, Bristol Myers Squibb) significantly improved PFS compared with chemotherapy in previously untreated patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer.
"In this study, the PFS at 2 years was 72%, so it was a significant improvement in PFS in this patient population at 2 years, which hopefully would translate to overall survival benefit," Barzi, a medical oncologist at City of Hope, said.
Reference:
- Andre T, et al. Abstract LBA768. Presented at: ASCO Gastrointestinal Cancers Symposium; Jan. 18-20, 2024; San Francisco.
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Disclosures:
Barzi reports no relevant financial disclosures.