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December 08, 2023
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Breast cancer prevention pioneer honored with lecture award

Fact checked byMindy Valcarcel, MS
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Jack Cuzick, PhD, received the William L. McGuire Memorial Lecture Award at this year’s San Antonio Breast Cancer Symposium.

The award recognizes Cuzick for his contributions to the prevention and treatment of breast cancer, as well as his commitment to transdisciplinary collaboration and leadership in the field.

Graphci with quote from Jack Cuzick, PhD

“I am very honored to receive this award. It has been a long but immensely satisfying journey from pure mathematics to cancer prevention,” Cuzick said in a press release. “Substantial progress has been made, but breast cancer is still the most common cancer in women, and there’s a lot more to be done.”

Cuzick is head of the cancer prevention unit in the Centre for Prevention, Detection and Diagnosis and John Snow professor of epidemiology at Queen Mary University of London.

As a statistician working on prior cancer trials, Cuzick noticed patients with breast cancer who received adjuvant tamoxifen exhibited reduced incidence of second cancer in the opposite breast.

This observation prompted Cuzick to propose prophylactic tamoxifen for women at increased risk for breast cancer. He subsequently led several trials that confirmed tamoxifen can reduce breast cancer risk.

Cuzick also helped develop the Tyrer-Cuzick breast cancer risk prediction model, and data from one of the trials he led identified mammographic density as a modifiable risk biomarker.

“Dr. Cuzick is a renowned scientist whose research has benefited innumerable patients,” Virginia Kaklamani, MD, co-director of SABCS, said in the release. “His impact in the field of prevention and treatment of early-stage breast cancer is felt every day in our clinic.”