Fact checked byMark Leiser

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May 06, 2023
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Triplet therapy effective for metastatic prostate cancer subset regardless of disease volume

Fact checked byMark Leiser

Treatment intensification with darolutamide plus androgen deprivation therapy and docetaxel improved OS among men with metastatic hormone-sensitive prostate cancer regardless of disease volume or risk, according to study results.

The benefits of early treatment intensification appeared consistent among men with high-volume or low-volume disease, as well as those with high-risk or low-risk disease, a secondary analysis of the randomized phase 3 ARASENS trial presented at ASCO Genitourinary Cancers Symposium and published in Journal of Clinical Oncology showed.

Healio spoke with Maha H. A. Hussain, MD, FACP, FASCO — deputy director and leader of the genitourinary oncology program at Robert H. Lurie Comprehensive Cancer Center at Northwestern University Feinberg School of Medicine, as well as a Healio | HemOnc Today Editorial Board member — about the findings and their implications.