Review of meeting abstracts shows toxicity reporting inconsistent, incomplete
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Toxicity reporting in certain abstracts presented in recent years at ASH Annual Meeting and Exposition appeared inconsistent and incomplete, according to a systematic review.
In many cases, toxicity reporting was absent from abstracts, results showed.
Researchers — who reviewed abstracts that highlighted phase 3 clinical trials in acute leukemia presented at ASH from 2017 to 2012 — often observed “formal toxicity minimization” and subjective terms to minimize toxicity.
Healio spoke with Lisa K. Hicks, MD, MSc, associate professor at University of Toronto and hematologist at St. Michael’s Hospital, about the findings and their potential implications.