Analysis identifies 50 new genetic variants linked to colorectal cancer risk
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Multiomic analysis has provided new insights into the genetics of colorectal cancer and how genetic variants contribute to disease risk and development.
Investigators analyzed more than 100,000 colorectal cancer cases and compared genomic data with more than 150,000 controls without colorectal cancer. The analysis included individuals of European and East Asian ancestries.
Their findings revealed 205 genetic variants that contribute to colorectal cancer risk, 50 of which had been previously unreported.
Healio spoke with researcher Stephen Gruber, MD, PhD, MPH, vice president of City of Hope National Medical Center and director of Center for Precision Medicine at City of Hope, about the findings and their potential implications.
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