January 04, 2023
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Bendamustine lymphodepletion effective, safe as part of CAR-T for advanced lymphoma
NEW ORLEANS — Bendamustine lymphodepletion resulted in significant CAR T-cell expansion among patients with relapsed or refractory non-Hodgkin lymphoma, according to study results presented at ASH Annual Meeting and Exposition.
The approach also appeared safe, with low incidence of high-grade neutropenia.
Healio spoke with researcher Saurabh Dahiya, MD, FACP, associate professor of medicine at Stanford Medicine, about the findings and their potential implications, particularly in light of an ongoing fludarabine shortage.
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Source:
Bharadwaj S, et al. Abstract 4657. Presented at: ASH Annual Meeting and Exposition; Dec. 10-13, 2022; New Orleans.
Disclosures:
Dahiya reports no relevant financial disclosures.