VIDEO: Understanding the ‘pivotal role’ NF-cappaB plays in myeloproliferative neoplasms

ByJohn O. Mascarenhas, MD

ByMarley V. Ghizzone

Fact checked byMindy Valcarcel, MS

In this video, John O. Mascarenhas, MD, highlighted a presentation that explored the science driving clinical development.

The talk, given by Steven T. Oh, MD, was presented at 14th International Congress on Myeloproliferative Neoplasms.

“His science and his laboratory research has highlighted the importance and pivotal role of NF-cappaB, and targeting that specifically,” Mascarenhas, professor of medicine at Icahn School of Medicine at Mount Sinai, director of Center of Excellence for Blood Cancer and Myeloid Disorders, and member of Tisch Cancer Institute, said.

Reference:

Oh ST. Leveraging inflammatory cytokine signaling for therapeutic benefit in MPNs. Presented at: 14th International Congress on Myeloproliferative Neoplasms; Oct. 27-28, 2022; Brooklyn, New York.

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Sources/Disclosures

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Healio Interviews

Disclosures: Mascarenhas reports serving as a consultant for AbbVie, Bristol Myers Squibb, Celgene, Constellation, CTI Biopharma, Galecto, Geron, GSK, Incyte, Kartos, Karyopharm, Novartis, PharmaEssentia, Roche and Sierra Oncology; and receiving funding paid to his institution from AbbVie, Bristol Myers Squibb, Celgene, CTI Biopharma, Geron, Incyte, Kartos, Merck, Novartis, PharmaEssentia and Roche.

Discoveries in Myeloproliferative Neoplasms

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VIDEO: Understanding the ‘pivotal role’ NF-cappaB plays in myeloproliferative neoplasms

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