VIDEO: Addition of abiraterone improves overall survival in two prostate cancer studies
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In this video, Ben Tran, MD, discusses the PEACE-1 and STAMPEDE studies that looked at the addition of abiraterone acetate plus prednisolone (AAP) to standard therapy, which was found to improve survival vs. standard therapy.
"These two studies change standard of care for me," said Tran, a medical oncologist at Peter MacCallum Cancer Centre in Melbourne, Australia.
"In high-volume de novo metastatic prostate cancer, I will now lean towards a triplet of docetaxel, abiraterone and [androgen deprivation therapy (ADT)], and in patients [without metastatic disease] who meet the criteria, I would consider abiraterone for two years in conjunction with ADT," Tran said.