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June 17, 2020
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VIDEO: Investigational antibody-drug conjugate shows promise in breast cancer

In this video, Jame Abraham, MD, director of breast oncology at Cleveland Clinic, spoke about the phase 1 study of the investigational antibody-drug conjugate SGN-LIV1A (Seattle Genetics) for metastatic breast cancer, presented at ASCO20Virtual Scientific Program.

“We are excited about the potential of this drug, though this is an early phase of the trial,” Abraham told Healio. “This is a dose-escalation study ... where we’re trying to find the optimal dose, safety and then effect profile from this work.”

Abraham said he looks forward to moving on to a phase 2 study to investigate the drug’s efficacy once the optimal dose is determined.