September 18, 2017
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Roswell Park Cancer Institute joins ORIEN consortium

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Michael A. Caligiuri
Candace S. Johnson

Roswell Park Cancer Institute has joined the Oncology Research Information Exchange Network, a research partnership that includes 16 of the top cancer centers in North America.

The network, known as ORIEN, formed in 2014 to share information and translate pooled resource into personalized cancer treatments.

Participating organizations have committed to contribute to a shared databank and collaborate on clinical research to accelerate the development of new treatments.

“In order to bring exceptional oncology care to patients — care that is precise, less toxic and achieves durable responses — you must be able to show the evidence that the treatment will have the right impact,” Michael A. Caligiuri, MD, ORIEN co-founder, director of The Ohio State University Comprehensive Cancer Center, and CEO of The James Cancer Hospital and Solove Research Institute, said in a press release. “Such evidence can only be developed through research. When cancer centers work together to gather larger groups of patients with similar disease, we can conduct more meaningful research — faster, which will help us make the discoveries that impact people at the bedside.”

ORIEN allows clinicians and researchers at member centers to leverage multiple data sources and match patients to targeted treatments. Partner centers use a common protocol, known as Total Cancer Care, to track the molecular, clinical and epidemiological data of consenting patients throughout their lifetimes. The resulting databank represents one of the world’s largest clinically annotated cancer tissue repositories, comprising data from more than 200,000 participating patients.

“‘Team science’ is a concept medical research centers work hard to nurture within our own institutions, but we haven’t always done a great job of making it work on a broader scale,” Candace S. Johnson, PhD, Roswell Park President and CEO, said in the release. “ORIEN is a network of centers committed to supporting and relying on one another, recognizing that collaboration is the key to driving our science forward and making a difference for patients. We couldn’t be prouder to help support and enhance this team effort.”