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Mohs' micrographic surgery effective for primary mucinous carcinoma of skin
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Mohs' micrographic surgery appeared to reduce recurrence rates and improve outcomes in patients with primary mucinous carcinoma of the skin, according to study results.
“Primary mucinous carcinoma of the skin [PMCS] is an uncommon subtype of sweat gland carcinoma, with only about 150 cases described in literature to date,” Jerry D. Brewer, MD, and colleagues wrote in the study.
Jerry D. Brewer
The researchers retrospectively reviewed medical records and histological slides to initially identify 10 patients with PMCS from January 1992 to December 2012 at Mayo Clinic, Rochester, Minn. Ovid Medline and PubMed were searched for relative publications involving PMCS.
Six of the patients identified met WHO criteria for PMCS, and the average age at diagnosis was 65 years. Four of the cases involved the face, and two involved the scalp. All tumors were confined within the dermis and ranged in size from 0.5 cm to 2.0 cm, according to the researchers.
During diagnosis, there was no evidence of metastatic melanoma adenocarcinoma documented. Mohs' micrographic surgery was conducted on five patients, and wide local excision was used to treat one patient.
During the median follow-up of 20 months, no recurrence or metastases occurred, according to the researchers.
The researchers concluded that Mohs' micrographic surgery could be used in areas of recurrent PMCS, as well as in cases where tissue conservation may be necessary.
Disclosures: The researchers report no relevant financial disclosures.
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