Gastroenterology News

A novel immunotherapy approach for solid, epithelial cancers reduced tumor burden among multiple patients with metastatic colon cancer, according to phase 2 study results.

The FDA has updated the label indication for Livmarli for the treatment of cholestatic pruritus in patients with progressive familial intrahepatic cholestasis, expanding the patient population to include infants aged 12 months and older.

Researchers found associations between Index of Severity for Eosinophilic Esophagitis scores and select clinical features across categories of disease severity, according to a study published in The Journal of Allergy and Clinical Immunology.

Remaining current on screening for hepatocellular carcinoma correlated with a “survival benefit” in older adults with hepatitis C virus-related cirrhosis who achieved viral cure but later developed HCC, according to researchers.

Patients with severe obesity undergoing Roux-en-Y gastric bypass for weight loss demonstrated greater reductions in blood lipids at 6 weeks vs. those on a very low-energy diet, according to study results in JAMA Surgery.

Women with polycystic ovary syndrome and high androgen levels may have a higher risk for liver disease than those with PCOS and normal androgen levels, according to an analysis of UK Biobank data.

Patients with acute gastroenteritis had up to fourfold increased odds for developing postinfection irritable bowel syndrome or functional dyspepsia, with a higher risk associated with proinflammatory microbes and SARS-CoV-2, data showed.

Multimodal intestinal ultrasound performed at 24 weeks can provide “useful information” for predicting endoscopic response at 1 year in patients with active Crohn’s disease initiating treatment with Stelara, according to researchers.

In a dose-dependent manner, fazirsiran reduced serum and liver concentrations of Z-AAT and also improved histological measures in patients with homozygous ZZ alpha-1 antitrypsin deficiency-associated liver disease, according to data.

Findings from a study that identified differences in the gut microbiota of children with autism indicate that stool sample testing could be used as an early, noninvasive diagnostic tool for autism, researchers reported.