Gastroenterology News

LOS ANGELES — A computer prompt recommending appropriate antibiotic use based on a patient’s level of risk for a resistant infection cut the use of extended-spectrum antibiotics for abdominal infections by around one-third in a large trial.

The FDA approved Vyloy with chemotherapy to treat locally advanced unresectable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinoma in adults, according to a press release.

Patients treated with denifanstat 50 mg vs. placebo achieved significant improvements in metabolic dysfunction-associated steatohepatitis resolution and fibrosis, according to study results in The Lancet Gastroenterology & Hepatology.

More patients with moderate to severe Crohn’s disease achieved histologic response at week 52 with mirikizumab vs. ustekinumab, regardless of prior biologic exposure, according to data presented at UEG Week.

Patients with metastatic gastrointestinal cancer may not need a 5-FU bolus as part of their treatment, according to retrospective study results.

The largest retailer in the nation has sampled a taste of the autoimmune specialty pharmacy market, and has decided it wants more.

Changes in MRI-derived markers of iron-corrected T1 mapping and liver fat content appear effective at predicting histological response among patients treated for metabolic dysfunction-associated steatohepatitis, according to researchers.

Treatment with Rinvoq resulted in higher rates of closure of external openings and drainage resolution vs. placebo in perianal fistulizing Crohn’s disease, according to pooled data from the U-EXCEL, U-EXCEED and U-ENDURE trials.

An invitation to screen for Helicobacter pylori along with fecal immunochemical testing did not significantly reduce gastric cancer incidence or mortality over approximately 5 years vs. FIT alone, according to a study conducted in Taiwan.

In our prior blog post, we discussed the frequent need to separate, from a legal and financial perspective, the real property from the practice in order to consummate a practice transaction with a private equity buyer.