Stomach/Duodenum News

Adults with obesity who tested positive for COVID-19 were significantly less likely to experience severe disease complications if they had previous bariatric surgery, according to findings from a matched-cohort analysis.

Gut microbiota-specific immunoglobulin A cells acted as a systemic mediator in MS, according to findings published in Science Immunology — findings that also suggest “a critical role” for mucosal B cells during active neuroinflammation.

The incidence of asthma in children declined 26% from 2000 to 2014 in British Columbia, Canada, and researchers have linked the decrease to reductions in early antibiotic exposure, mediated by changes in gut microbiota.

During this year’s ACG 2020 Virtual meeting, Healio will host its annual Disruptive Innovators Award ceremony on Monday, October 26.

In this podcast episode, we interview Barry Marshall, AC, FRACP, FRS, FAA, the legendary Nobel Laureate who discovered that peptic ulcer disease was caused by the bacteria Helicobacter pylori, not excess acid.

Baseline features of gastroparesis, identified with gastric motility testing, may help identify patient risk for more severe longitudinal symptoms and worse quality of life, according to study results.

Helicobacter pylori is a gram-negative, spiral, flagellated organism that infects the gastric mucosa, leading to chronic gastritis. It has been causally related to duodenal and gastric ulcers, gastric cancer, and gastric mucosa associated lymphoid tissue (MALT) lymphoma.

Changes in the human gut microbiome after sleeve gastrectomy contribute to the negative skeletal impact of bariatric surgery among adults with obesity, according to a speaker.

All available proton pump inhibitors (PPIs) are indicated for once-daily dosing, usually in the morning. Although food has different effects on the bioavailability of each molecule and meal timing may not affect bioavailability of rabeprazole or pantoprazole, it is my practice to recommend that all PPIs be given prior to meals for optimal efficacy. This is based on the concepts outlined in Question 15 and results of an intragastric pH study performed in our laboratory in which significantly superior daytime pH control (time intragastric pH >4) was seen when the PPI was taken before breakfast, compared to an empty stomach in the morning with no food until noon (Figure 16-1).

In hospitalized patients with COVID-19, famotidine was correlated with a lower mortality risk, lower risk for combined mortality and intubation outcomes and lower serum markers for severe disease, according to a study published in the American Journal of Gastroenterology.