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Motility News
VIDEO: Talley discusses David Sun lecture on advances in functional GI disorders
LAS VEGAS — In this exclusive video, Nicholas J. Talley, MD, PhD, professor of medicine and pro vice-chancellor of global research at the University of Newcastle, Australia, discusses the David Sun Lecture, which he delivered at ACG 2016. This distinguished lecture focused on new developments in functional gut disorders.
Naldemedine relieves opioid-induced constipation within 4 hours
LAS VEGAS — Naldemedine induced spontaneous bowel movements more quickly than placebo — often within 4 hours of first dose — and maintained its efficacy for 12 weeks, according to data presented at ACG 2016.
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VIDEO: Saltzman highlights ACG presidential plenary
LAS VEGAS — In this exclusive video from ACG 2016, John R. Saltzman, MD, FACG, director of endoscopy at Brigham and Women’s Hospital, professor of medicine at Harvard Medical School, and Chair of Educational Affairs for ACG, discusses several presentations delivered at the presidential plenary session.
Emend improves gastroparesis symptoms, fails to reach endpoint
LAS VEGAS — Oral Emend improved gastroparesis symptoms based on commonly used gastroparesis measures in a randomized controlled trial, according to the APRON results presented at ACG 2016.
Amitiza improves abdominal pain, bloating in IBS-C
Researchers showed superiority of Amitiza over placebo for improving abdominal pain, bloating and composite endpoints including stool frequency in patients with constipation-predominant irritable bowel syndrome, according to post hoc analyses of two pivotal phase 3 randomized controlled trials.
Intussusception hospitalizations rise in some infants after initial RV vaccination
A spike in intussusception hospitalization rates occurred in children aged 8 to 11 weeks after children received initial doses of RotaTeq or Rotarix vaccine for rotavirus compared with prevaccine years, according to recent study results.
Opioid-induced constipation medication may improve OS in advanced cancer
Treatment with and response to methylnaltrexone for opioid-induced constipation appeared associated with improved OS in patients with advanced cancers, according to a post-hoc analysis of two randomized trials.
Migraine associated with functional GI disorders in children, adolescents
In children and adolescents, migraine headaches are positively associated with functional dyspepsia, irritable bowel syndrome and abdominal migraine, and negatively associated with functional constipation, investigators from a European case-control study found.
Acupuncture safe, effective for treatment of chronic severe functional constipation
Electroacupuncture increased complete spontaneous bowel movements within 8 weeks, according to findings published in the Annals of Internal Medicine.
COMPOSE III: Naldemedine safe for long-term treatment of OIC
Naldemedine was safe and well tolerated through 52 weeks for treating opioid-induced constipation in patients with chronic noncancer pain, according to research presented at PAINWeek 2016.
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