Liver/Biliary Disorders News

DALLAS — New data presented at ObesityWeek demonstrate an encouraging early profile of an investigational dual GLP-1/GIP receptor agonist in healthy adults, according to a speaker at ObesityWeek.

Individuals with low birthweight or born small for gestational age were significantly more likely to develop nonalcoholic fatty liver disease later in life, with additionally higher odds for more severe NAFLD, according to data at UEG Week.

Liver Cancer Awareness Month, celebrated every October, seeks to raise awareness about the third deadliest cancer in the United States, with approximately 41,000 new cases and as many as 30,000 deaths each year.

Although the use of robotic-assisted cholecystectomy increased 37-fold from 2010 to 2019, the procedure was associated with significantly higher rates of bile duct injury compared with laparoscopic cholecystectomy, according to research.

Elevated serum triglyceride levels were associated with severity of acute pancreatitis and risk for related complications, including organ failure, among patients with nonalcoholic fatty liver disease, according to data.

Subcutaneous pegozafermin at weekly and biweekly doses improved fibrosis at 24 weeks vs. placebo among patients with biopsy-confirmed nonalcoholic steatohepatitis, supporting the therapy’s advancement to phase 3 development, data showed.

Dietary supplementation with resistant starch reduced intrahepatic triglyceride content and may help manage disease by altering gut microbiota among patients with nonalcoholic fatty liver disease, according to data in Cell Metabolism.

Liver disease was the primary cause of death in patients with alcohol-related liver disease several years after diagnosis, with the risk for mortality almost three times higher in those with decompensated cirrhosis, according to research.

Although fibrosis-4 index and NAFLD fibrosis score did not significantly differ in diagnosing advanced fibrosis in nonalcoholic fatty liver disease, fibrosis-4 may be a better screening tool in lean patients, according to a study.

Rates of hepatocellular carcinoma caused by alcohol-related disease and nonalcoholic fatty liver disease are on the rise, especially among Hispanic individuals, according to research in Clinical Gastroenterology and Hepatology.