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November 18, 2024
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CDC: 1 dead in multistate outbreak of E. coli linked to organic carrots

Liver/Biliary Disorders News

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November 18, 2024
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Novel farnesoid X receptor agonist safe, reduces liver fat content by up to 22.8% in MASH

Novel farnesoid X receptor agonist safe, reduces liver fat content by up to 22.8% in MASH

SAN DIEGO — Once-daily FXR314 was well-tolerated and safely improved liver fat content and biochemical markers over 16 weeks in patients with metabolic dysfunction-associated steatohepatitis, according to research at The Liver Meeting.

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November 18, 2024
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GLP-1RAs may offer ‘hepatoprotective’ benefit for diabetes, alcohol-related liver disease

GLP-1RAs may offer ‘hepatoprotective’ benefit for diabetes, alcohol-related liver disease

SAN DIEGO — Glucagon-like peptide-1 receptor agonists may help alleviate risk for adverse liver outcomes, particularly hepatic decompensation, among patients with type 2 diabetes and alcohol-associated liver disease.

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AdobeStock_Carrots_1200x630
November 18, 2024
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CDC: 1 dead in multistate outbreak of E. coli linked to organic carrots

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November 17, 2024
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Mean arterial pressure target of 75 mmHg may boost survival in cirrhosis with septic shock

Mean arterial pressure target of 75 mmHg may boost survival in cirrhosis with septic shock

SAN DIEGO — Increasing the mean arterial pressure target to 75 mmHg lowered the odds of 28-day mortality by 85%, and also reduced the odds of acute kidney injury nonrecovery, in decompensated cirrhosis with septic shock, according to data.

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November 17, 2024
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Resuming antiviral therapy after withdrawal does not affect HBsAG seroclearance in HBV

Resuming antiviral therapy after withdrawal does not affect HBsAG seroclearance in HBV

SAN DIEGO — Retreatment with nucleos(t)ide analogue therapy for relapse after withdrawal did not affect hepatitis B surface antigen seroclearance among patients with chronic HBV infection, according to a researcher at The Liver Meeting.

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November 17, 2024
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Early renal replacement therapy improves survival in acute liver failure, cerebral edema

Early renal replacement therapy improves survival in acute liver failure, cerebral edema

SAN DIEGO — Preemptive continuous renal replacement therapy after therapeutic plasma exchange reduced mortality and improved other outcomes in patients with acute liver failure and cerebral edema, according to data from The Liver Meeting.

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November 15, 2024
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Mycophenolate ‘comparable, if not better’ than azathioprine for autoimmune hepatitis

Mycophenolate ‘comparable, if not better’ than azathioprine for autoimmune hepatitis

PHILADELPHIA — Mycophenolate mofetil appeared to be more efficacious and tolerable than azathioprine in patients with autoimmune hepatitis, especially among those aged older than 50 years and with lower IgG levels, according to a presenter.

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November 14, 2024
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VIDEO: Green tea extract, turmeric among supplements associated with liver injury

VIDEO: Green tea extract, turmeric among supplements associated with liver injury

PHILADELPHIA — In this video, Nancy S. Reau, MD, FAASLD, AGAF, discusses the impact certain herbal and dietary supplements may have on the liver, especially among patients with underlying liver disease.

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November 14, 2024
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Pharmacotherapy for alcohol use disorder ‘underutilized’ in at-risk populations

Pharmacotherapy for alcohol use disorder ‘underutilized’ in at-risk populations

PHILADELPHIA — Pharmacologic therapy for alcohol use disorder may be an “underutilized treatment modality,” especially in patients with related liver disease, according to research presented at the ACG Annual Scientific Meeting.

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November 14, 2024
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VIDEO: ‘Encouraging’ safety data on Livdelzi in primary biliary cholangitis, cirrhosis

VIDEO: ‘Encouraging’ safety data on Livdelzi in primary biliary cholangitis, cirrhosis

PHILADELPHIA — In this video, Nancy S. Reau, MD, FAASLD, AGAF, highlights a presentation at the ACG Annual Scientific Meeting investigating the use of Livdelzi in patients with primary biliary cholangitis and cirrhosis.

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November 13, 2024
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VIDEO: Treating autoimmune hepatitis with mycophenolate ‘still a cautionary tale’

VIDEO: Treating autoimmune hepatitis with mycophenolate ‘still a cautionary tale’

PHILADELPHIA — In this video, Nancy S. Reau, MD, FAASLD, AGAF, speaks with Healio about findings from a systemic review and meta-analysis on the efficacy of mycophenolate mofetil compared with azathioprine for autoimmune hepatitis.

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