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Liver/Biliary Disorders News
Noninvasive tests identify candidates for Rezdiffra, predict response in patients with MASH
WASHINGTON — Researchers have determined that several noninvasive tests could help identify candidates for treatment with Rezdiffra, as well as predict response, in metabolic dysfunction-associated steatohepatitis.
BLOG: Predicting sinusoidal obstructive syndrome after allogeneic stem cell transplantation
Sinusoidal obstructive syndrome is a rare but potentially serious complication that can occur after hematopoietic stem cell transplantation.
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Survodutide upholds ‘promising’ reduced liver fat, fibrosis biomarkers in MASH at 28 weeks
WASHINGTON — Survodutide sustained improvement in liver fat content, liver enzymes and fibrosis biomarkers in patients with metabolic dysfunction-associated steatohepatitis at 28 weeks, according to a late-breaking abstract presented here.
Prevalence of advanced fibrosis similar in lean, non-lean MASLD, linked to genetic risk
WASHINGTON — The risk for advanced fibrosis was similar among patients with lean and non-lean metabolic dysfunction-associated steatotic liver disease and may be associated with genetic risk, according to data at Digestive Disease Week.
Larsucosterol rebounds to snag FDA breakthrough status for alcohol-related hepatitis
The FDA has granted breakthrough therapy designation to Durect’s larsucosterol for the treatment of patients with severe alcohol-associated hepatitis, despite mixed results from previously released topline data.
Statin use linked to ‘sharp 86% risk reduction’ for primary sclerosing cholangitis in IBD
WASHINGTON — Statin use was associated with up to a 90% risk reduction for new-onset primary sclerosing cholangitis among patients with inflammatory bowel disease, according to data presented at Digestive Disease Week.
Parental obesity linked to up to 55% increased risk for MASLD among adult offspring
WASHINGTON — Parental obesity was associated with a nearly threefold increased risk for metabolic dysfunction-associated steatotic liver disease among offspring in early adulthood, according to data presented at Digestive Disease Week.
Bariatric surgery associated with lower mortality, health care cost in patients with MASLD
WASHINGTON — Bariatric surgery was associated with improved clinical outcomes and more cost-effective health care resource utilization among patients with metabolic dysfunction-associated steatotic liver disease, according to data.
‘Encouraging’ data: GLP-1RAs linked to lower risk for cirrhosis in MASLD, type 2 diabetes
WASHINGTON — Glucagon-like peptide-1 receptor agonists were associated with lower risk for progression to cirrhosis and hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease and type 2 diabetes.
GLP-1RA use in MAFLD, obesity lowers mortality, ‘provides cardiovascular benefits’
WASHINGTON — Patients with obesity and metabolic dysfunction-associated fatty liver disease taking glucagon-like peptide-1 receptor agonists had lower risk for all-cause mortality and major cardiovascular events, according to a presenter.
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Headline News
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Headline News
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Headline News
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