Liver/Biliary Disorders News

Terns Pharmaceuticals Inc. announced positive topline results from the phase 2a Lift study of TERN-101 for the treatment of patients with nonalcoholic steatohepatitis.

Among patients hospitalized with COVID-19, liver impairment appeared within the first days of admission; virus severity also correlated with abnormality in liver function tests.

Extending dosing of a novel GalNAc-small interfering RNA brought most patients’ surface antigen levels of hepatitis B virus under control, according to a presenter at the International Liver Congress.

Endoscopic sleeve gastroplasty in patients with nonalcoholic steatohepatitis vs. life-style intervention alone was safe and effective for achieving weight loss correlated with significant improvements, according to a presentation at the International Liver Congress.

Peer support within marginalized groups at risk for hepatitis C virus increased treatment initiation and completion as well as improved outcomes, according to a presenter at The International Liver Congress.

Among patients with FIB-4 nonalcoholic steatohepatitis at greater risk for progression to end stage liver disease, researchers at the International Liver Congress found efruxifermin 50 mg was safe and well-tolerated.

Researchers found Latin American countries with more alcohol policies had lower alcohol consumption per capita, deaths due to traffic injuries and alcohol-associated cirrhosis, according to a presenter at the International Liver Congress.

Using a novel RNA interference therapeutic improved fibrosis and reduced toxic proteins and globular burden in alpha-1 antitrypsin deficiency, according to a presenter at the International Liver Congress.

A study from Israel, where vaccination for COVID reached most of the population older than 16 years, showed older patients, post-transplant patients and those with advanced liver disease produced less immune response to the Pfizer COVID-19 vaccine.

Among patients with nonalcoholic fatty liver disease and advanced fibrosis, food insecurity significantly correlated with greater all-cause mortality, according to a presenter at the International Liver Congress.