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November 18, 2024
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CDC: 1 dead in multistate outbreak of E. coli linked to organic carrots

Liver/Biliary Disorders News

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October 17, 2024
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Multiparametric MRI liver biomarkers predict those ‘likely to achieve’ MASH resolution

Multiparametric MRI liver biomarkers predict those ‘likely to achieve’ MASH resolution

Changes in MRI-derived markers of iron-corrected T1 mapping and liver fat content appear effective at predicting histological response among patients treated for metabolic dysfunction-associated steatohepatitis, according to researchers.

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October 11, 2024
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Waitlist priority, quality donors tied to better outcomes in pediatric acute liver failure

Waitlist priority, quality donors tied to better outcomes in pediatric acute liver failure

Over three decades, changes to organ allocation policies were associated with reduced waitlist mortality and increased rates of liver transplant among children with pediatric acute liver failure, according to research in JAMA Surgery.

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AdobeStock_Carrots_1200x630
November 18, 2024
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CDC: 1 dead in multistate outbreak of E. coli linked to organic carrots

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October 10, 2024
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Drug rivals face off in PBC after FDA hands down 2 new approvals, 1 advisory snub

Drug rivals face off in PBC after FDA hands down 2 new approvals, 1 advisory snub

The long-stagnant primary biliary cholangitis drug market has seen renewed attention in the past 3 months with the addition of two FDA-approved therapy options as well as a costly ruling from an FDA advisory committee.

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October 10, 2024
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Hispanic, Asian populations in US at highest risk for alcohol-associated liver disease

Hispanic, Asian populations in US at highest risk for alcohol-associated liver disease

Significant differences in alcohol use, alcohol-related mortality and liver transplant rate by race and ethnicity underscore the need for “tailored approaches to managing” alcohol-related liver disease in the U.S., according to a researcher.

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October 09, 2024
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Immunotherapy may make transplant possible in late-stage liver cancer

Immunotherapy may make transplant possible in late-stage liver cancer

Immunotherapy treatment may make liver transplant viable for patients with later-stage hepatocellular carcinoma provided they adhere to a 3-month waiting period, according to study results.

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October 08, 2024
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FDA grants breakthrough designation to survodutide for treatment of MASH

FDA grants breakthrough designation to survodutide for treatment of MASH

The FDA has granted breakthrough therapy designation to Boehringer Ingelheim’s survodutide for the treatment of adult patients with noncirrhotic metabolic dysfunction-associated steatohepatitis and moderate or advanced fibrosis.

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October 08, 2024
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‘Call to action’: Variation in cirrhosis infections support streamlined antibiotic use

‘Call to action’: Variation in cirrhosis infections support streamlined antibiotic use

Significant variations in global rates of infection, culture-positivity and drug resistance serve as a “call to action” to streamline antibiotic use and improve outcomes among inpatients with cirrhosis, according to researchers.

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October 04, 2024
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Hepatic steatosis identified in more than half of younger adults without history of MASLD

Hepatic steatosis identified in more than half of younger adults without history of MASLD

Hepatic steatosis was prevalent among 52% of adults with or without type 2 diabetes and no known history of metabolic dysfunction-associated steatotic liver disease, according to findings published in Obesity.

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October 03, 2024
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FDA grants breakthrough status to Sagimet’s denifanstat to treat MASH with fibrosis

FDA grants breakthrough status to Sagimet’s denifanstat to treat MASH with fibrosis

The FDA granted breakthrough designation to Sagimet Biosciences’ denifanstat for the treatment of patients with metabolic dysfunction-associated steatohepatitis and moderate to advanced fibrosis, according to a company press release.

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October 02, 2024
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Mental health concerns reduce likelihood of hepatology referral in alcohol use disorder

Mental health concerns reduce likelihood of hepatology referral in alcohol use disorder

Nearly two-thirds of patients with excessive alcohol use and a high fibrosis-4 index were not referred for liver-related care, with fewer referrals among those with mental health disorders or alcohol-related mental health hospitalizations.

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