Liver/Biliary Disorders News

Patients who received obeticholic acid for primary biliary cholangitis experienced greater transplant-free survival compared with external control patients, according to research published in Gastroenterology.

A patient outcomes simulator found that non-liver-related mortality could surpass liver-related mortality in patients with nonalcoholic fatty liver disease, depending on age and fibrosis stage at diagnosis, noted data in JAMA Network Open.

People with HIV and untreated hepatitis C virus have an 85% higher risk for type 1 MI per each 10-year increase in age, researchers reported.

Second- and third-generation individuals of Mexican descent who reside in the U.S. had a higher risk for developing hepatocellular carcinoma than first-generation U.S. Mexicans, according to study results.

Higher state-level geographic density of gastroenterologists was linked with decreased mortality from alcohol-associated liver disease in adults aged 25 years or older, according to new data in Clinical Gastroenterology and Hepatology.

Investigators have identified an elevated risk for hepatocellular carcinoma in people exposed to per- and polyfluoroalkyl substances, according to a study published in JHEP Reports.

The FDA has approved Xenpozyme as the first treatment for patients with acid sphingomyelinase deficiency with symptoms unrelated to the central nervous system.

Fazirsiran effectively reduced the production and accumulation of a protein that causes alpha-1 antitrypsin deficiency and subsequent liver fibrosis in a small subset of patients, according to data in The New England Journal of Medicine.

Despite increased perioperative risks in older patients with hepatocellular carcinoma and cirrhosis, orthotropic liver transplantation provides greater survival benefit compared with ablative therapies, according to new research.

Evening chronotype was associated with more severe nonalcoholic fatty liver disease independent of age, sex and BMI compared with morning chronotype among adults with obesity, according to data published in International Journal of Obesity.