Liver/Biliary Disorders News

BOSTON — Triple combination of vebicorvir, imdusiran and nucleos(t)ide reverse transcriptase inhibitor did not improve markers of active hepatitis B infection in virologically suppressed patients vs. treatment regimens without vebicorvir.

BOSTON — An intensive, advanced practice provider-guided weight loss program helped patients with metabolic dysfunction-associated steatotic liver disease achieve statistically significant weight loss vs. standard of care.

BOSTON — Researchers recommended the FibroScan-aspartate aminotransferase score as a noninvasive biomarker to stratify patients at risk for metabolic dysfunction-associated steatohepatitis, when used with different cutoff points for HbA1C.

BOSTON — A new model forecasted a “substantial clinical burden” of metabolic dysfunction-associated steatotic liver disease in the next 30 years, including twice as many cases of liver cancer and triple the need for liver transplantation.

BOSTON — Food insecurity in adolescents is “very tightly associated” with metabolic dysfunction-associated steatotic liver disease, which may result from not being able to eat or purchase a balanced meal, according to a researcher.

VANCOUVER, British Columbia — With alcohol-related disease still on the rise after surging during the COVID-19 pandemic, an expert here discussed treatment options, including liver transplantation, for patients with alcoholic hepatitis.

Patients with acute-on-chronic liver failure and recompensated cirrhosis had less severe disease, lower incidence of respiratory failure and better prognosis at 1 year vs. those with decompensated cirrhosis, researchers reported.

Twelve months of testosterone replacement therapy did not improve metabolic dysfunction-associated steatotic liver disease in a group of older men with hypogonadism, according to a secondary analysis of the T Trials.

VANCOUVER, British Columbia — Despite recent changes in nomenclature for metabolic dysfunction-associated steatotic liver disease, an expert here noted that clinical pathways largely remain the same and require reinforcing.

VANCOUVER, British Columbia — Substituting just one meat-based meal with protein from plant or dairy sources could improve metabolite signatures linked to hepatic encephalopathy in patients with cirrhosis, according to a presenter here.