Irritable Bowel Syndrome News

Researchers showed superiority of Amitiza over placebo for improving abdominal pain, bloating and composite endpoints including stool frequency in patients with constipation-predominant irritable bowel syndrome, according to post hoc analyses of two pivotal phase 3 randomized controlled trials.

The results of a prospective cohort study showed that — in addition to acute gastrointestinal infection — female sex, vulnerability to diarrhea under stress, previous diarrhea, subjective somatic symptom burden and illness anxiety are all independently associated with the risk for developing irritable bowel syndrome.

In children and adolescents, migraine headaches are positively associated with functional dyspepsia, irritable bowel syndrome and abdominal migraine, and negatively associated with functional constipation, investigators from a European case-control study found.

VSL Pharmaceuticals has relocated manufacturing of its probiotic medical food VSL#3 back to Italy to remove all traces of dairy from the process, making it the only dairy-free probiotic medical food available, according to a press release.

Six-month data from a real-world surveillance study shows over-the-counter IBgard is safe and well-tolerated in patients with irritable bowel syndrome, according to a press release from the manufacturer.

Patients with Clostridium difficile infection have a high risk for developing post-infectious irritable bowel syndrome, particularly those with longer duration of C. difficile infection, anxiety and higher BMI, according to a recent study published in Alimentary Pharmacology and Therapeutics.

Synthetic Biologics today announced it has completed an End of Phase 2 meeting with the FDA for SYN-010, its microbiome-based anti-methane drug for the treatment of constipation-predominant irritable bowel syndrome.

A brain-to-gut pathway originating with psychological symptoms and a distinct gut-to-brain pathway originating with gut symptoms are both involved in patients with functional gastrointestinal disorders like irritable bowel syndrome and functional dyspepsia, according to recent study data.

A wealth of new data on dietary therapies for irritable bowel syndrome have been recently published in the journals and presented at scientific society meetings.

Modified low FODMAP rye bread improved symptom control in patients with irritable bowel syndrome in a randomized clinical trial.