Irritable Bowel Syndrome News

Tenapanor, an investigational, minimally systemic, small-molecule NHE3 inhibitor, was well tolerated and improved symptoms in patients with constipation-predominant irritable bowel syndrome in the first of two phase 3 clinical trials, the manufacturer Ardelyx announced.

CHICAGO — In this exclusive video from Digestive Disease Week, Mark Pimentel, MD, executive director of the Medically Associated Science and Technology program at Cedars Sinai, discusses his research on predicting response to Xifaxan in patients with irritable bowel syndrome.

CHICAGO — Trulance safely and effectively improved symptoms in patients with constipation-predominant irritable bowel syndrome, according to the results of two phase 3 clinical trials presented at Digestive Disease Week.

CHICAGO — Researchers found that while a low FODMAP diet is safe and effective in patients with irritable bowel syndrome, patients were often unable to recognize which specific foods triggered their symptoms. An expert here at Digestive Disease Week advised that the diet should be administered and carried out by an expert nutritionist.

CHICAGO — Fecal microbiota transplantation improved symptoms and quality of life in patients with irritable bowel syndrome, according to the results of a double blind randomized controlled trial presented at Digestive Disease Week.

CHICAGO — Individuals with irritable bowel syndrome in the general population are more likely to seek medical care if they are older, more frequently bloated, more concerned about their bowel function and more socially affected by their symptoms, according to research presented at Digestive Disease Week.

CHICAGO — Antigliadin antibodies may be a useful biomarker for predicting which patients with irritable bowel syndrome will improve on a gluten-free diet, according to research presented at Digestive Disease Week.

Randomized controlled trials of the low FODMAP diet for irritable bowel syndrome carry a high risk for bias and have insufficient follow-up, and the improvements in symptoms observed in these trials could be driven by a placebo response, according to new research published in Alimentary Pharmacology and Therapeutics.

Home-based hypnotherapy exercises on a CD were as effective as individual gut-directed hypnotherapy performed by a qualified therapist in children with irritable bowel syndrome or functional abdominal pain syndrome, according to the results of a randomized clinical trial.

April is IBS Awareness Month, first designated by the International Foundation for Functional Gastrointestinal Disorders in 1997 to spread awareness of the 10% to 15% of Americans who suffer from the symptoms of irritable bowel syndrome.