Intestinal Disorders News

Researchers have completed the first large-scale validation of anti-cytolethal distending toxin B and anti-vinculin antibodies as a mechanism-based biomarker for diarrhea-predominant irritable bowel syndrome, according to data released in advance of Digestive Disease Week.

A sustained period of intraoperative hypothermia in patients who underwent segmental colectomy was not associated with an increased risk for developing a surgical site infection compared with patients in whom perioperative normothermia was maintained, according to recent study data.

Measurement of fecal calprotectin effectively monitored recurrence of Crohn’s disease after intestinal resection, according to recent study data.

The risk for developing inflammatory bowel disease is significantly higher among first-, second- and third-degree relatives of patients with inflammatory bowel disease, particularly in younger family members, according to recent study data.

Constipation-predominant irritable bowel syndrome, or IBS-C, and chronic idiopathic constipation, or CIC, are not distinct diseases but rather exist on a spectrum where abdominal symptoms affect the most severe patients, according to recent study data.

Defecatory disorders such as constipation and fecal incontinence are commonly associated with pregnancy and the postpartum period, and they may cause significant patient stress and health care burden, according to a recently published review.

Results from a recent phase 3 study showed that Resolor is a safe, effective and well-tolerated treatment for men with chronic constipation.

The incidence of ischemic colitis has increased in recent decades and is most common in older patients with multiple comorbidities, according to findings from a retrospective population-based cohort and nested case-control study.

Combining a gastrointestinal microbiome modulator with metformin may help alleviate intestinal adverse effects commonly related to type 2 diabetes, according to research in the Journal of Diabetes Science and Technology.

A multidisciplinary panel of experts have written a guideline on the management of perianal fistulas associated with Crohn’s disease, a common manifestation that can result in significant morbidity.