Inflammatory Bowel Disease News

The FDA has issued a safety alert warning patients and health care providers of a “rare risk of intrahepatic cholestasis of pregnancy” linked to thiopurine use.

The FDA has approved a citrate-free, high-concentration formulation of the interchangeable adalimumab biosimilar Cyltezo to treat multiple chronic inflammatory diseases, according to the manufacturer.

In a Healio video exclusive, Megan Riehl, PsyD, AGAF, and Kate Scarlata, MPH, RDN, LDN, discuss their new book, “Mind Your Gut,” a comprehensive guide for treating irritable bowel syndrome from nutritional and behavioral perspectives.

A young woman, newly diagnosed with inflammatory bowel disease, sits in your office.

Pretreatment with budesonide did not significantly influence engraftment among patients with ulcerative colitis who underwent fecal microbiota transplantation, with researchers reporting that clinical response appeared to be donor-dependent.

The FDA has approved subcutaneous administration of Takeda Pharmaceuticals’ Entyvio for maintenance therapy in adult patients with moderate-to-severe Crohn’s disease following induction therapy via IV administration of the biologic.

Despite a class-wide black box warning for prescribing in the early setting, 31% of providers reported positioning Janus kinase inhibitors as first-line treatment among patients with severe ulcerative colitis, according to survey results.

In a Healio video exclusive, Edward V. Loftus Jr., MD, noted that although some concerns remain for switching patients between interchangeable biosimilars, data has continued to show acceptable outcomes as well as “increased access.”

If you see more than a few patients with inflammatory bowel disease, you likely already have been asked by a third-party payer to switch a patient’s adalimumab prescription from the reference product to a biosimilar.

The age of biosimilars has come for gastroenterology. This includes interchangeable products, three of which are now on the market. How this will impact patient care in the near and distant future is the subject of much speculation.