Hepatitis C News

Fixed dose treatment with sofosbuvir-velpatasvir-voxilaprevir with or without ribavirin for 12 weeks was effective and well-tolerated in patients with hepatitis C genotype 1 who had previously failed direct-acting antiviral therapy, according to a recent study.

Next-generation metagenomic sequencing, or NGMS, can potentially detect new viral infections in the blood that may be of medical importance, such as human hepegivirus-1, according to data published in Annals of Internal Medicine.

Viral eradication with direct-acting antivirals does not appear associated with an increased risk for liver transplant waitlist drop-out due to hepatocellular carcinoma progression in patients with hepatitis C, according to a recently published study.

Adding hepatitis C virus screening to an automated order set for patients with HIV greatly increased hepatitis testing at a Massachusetts clinic, according to researchers.

The European Center for Disease Prevention and Control recently published results of two semi-structured surveys that found a wide variation in existing national testing policy and lack of monitored data for hepatitis B and hepatitis C in the EU/EEA member states.

Results of a recently published prospective study showed that direct-acting antiviral therapy is effective in patients coinfected with hepatitis B and hepatitis C and most patients with HBV reactivation had later resolution.

An investigational fixed-dose combination regimen containing Sovaldi, velpatasvir and voxilaprevir for the treatment of hepatitis C virus resulted in high rates of SVR after 12 weeks of treatment among patients with or without compensated cirrhosis in whom previous therapy with direct-acting antiviral agents had failed, according to results of two international, phase 3 trials.

Treatment with Technivie plus ribavirin or Harvoni plus ribavirin were effective in patients with hepatitis C genotype 4, according to a recently published study.

Patients with hepatocellular carcinoma and hepatitis C were less likely to achieve sustained virologic response while receiving direct-acting antiviral therapy compared with patients without HCC, according to results of a retrospective study.

Treatment with generic ledipasvir-sofosbuvir for 8 to 12 weeks was affective in Chinese patients with hepatitis C genotype 1b, according to a recently published study.