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January 10, 2024
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VIDEO: Community-based care for homeless individuals with HCV achieves more than 80% SVR

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BOSTON — Nancy S. Reau, MD, FAASLD, AGAF, spoke with Healio about results from the END C study, which evaluated a community-based care model for hepatitis C virus infection among individuals at multiple community homeless sites in England.

According to results presented at The Liver Meeting, the study enrolled 418 individuals with a history of injection drug use, alcohol use disorder or prior incarceration. At 12 weeks, sustained virologic response rates were 81% in the intention-to-treat analysis.

“When we are trying to push our treatment into these more controversial or less stable populations, we are going to see slightly lower SVR rates, but that is still an incredibly high SVR rate,” Reau, professor and associate director of organ transplantation at Rush University, said. “We’re going to have to come up with more innovative care models.”