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November 29, 2022
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Pregnant people ‘the last frontier’ of treatment in HCV

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WASHINGTON — Although well-established and effective treatment protocols exist for most patients with hepatitis C virus infection, a presenter at The Liver Meeting said uncertainty remains when treating pregnant people with HCV.

“In my opinion, and I think some others would agree, this is really the last frontier of treatment in hepatitis C,” Tatyana Kushner, MD, associate professor in the division of liver diseases at the Icahn School of Medicine at Mount Sinai, told Healio in this video exclusive. “We have pretty well-developed guidelines and treatment protocols for virtually all other patient groups, but we don’t have clear recommendations for what to do with a pregnant person who has hepatitis C.”

In her lecture, Kushner discussed screening in children, especially those born to mothers with HCV; a phase 4 clinical trial (STORK) evaluating treatment of HCV in pregnant people; and a new CDC registry with data on direct-acting antiviral exposure in pregnancy.