June 03, 2021
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VIDEO: Cadherin-11 levels in Crohn’s do not prevent colitis associated colon cancer
In this video exclusive, Florian Rieder, MD, and Jiannan Li, MD, PhD, from Cleveland Clinic, discussed a study that looked at Cadherin-11 levels in patients with inflammatory bowel disease, in particular Crohn’s disease.
They said Cadherin-11 expression is increased in Crohn’s strictures. Prevention of Cadherin-11 reduces clinical severity and fibrosis of experimental colitis. However, it did not prevent colitis associated colon cancer.
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Source:
Li J, et al. Abstract 722. Presented at: Digestive Disease Week; May 21-24, 2021 (virtual meeting).
Disclosures:
Li reports no relevant financial disclosures.