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June 03, 2021
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VIDEO: Cadherin-11 levels in Crohn’s do not prevent colitis associated colon cancer

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In this video exclusive, Florian Rieder, MD, and Jiannan Li, MD, PhD, from Cleveland Clinic, discussed a study that looked at Cadherin-11 levels in patients with inflammatory bowel disease, in particular Crohn’s disease.

They said Cadherin-11 expression is increased in Crohn’s strictures. Prevention of Cadherin-11 reduces clinical severity and fibrosis of experimental colitis. However, it did not prevent colitis associated colon cancer.