January 29, 2021
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VIDEO: DUR-928 well tolerated at three doses for treatment of NASH
Issue: March 2021
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In this exclusive video, Eric Lawitz, MD, from the Texas Liver Institute, University of Texas Health, San Antonio, spoke about DUR-928, a daily oral treatment for nonalcoholic steatohepatitis.
DUR-928 was well tolerated at 50 mg, 150 mg and 300 mg, with no serious adverse events reported, according to Lawitz. At 4 weeks, the median liver fat reduction was –18% at 50 mg, –19% at 150 mg and –23 at 300 mg as measured by MRI-PDFF.
Lawitz said that DUR-928 showed overall improvement in multiple markers such as liver enzymes, liver imaging and serum lipid profiles.
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Sources/Disclosures
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Source:
Lawitz E, et al. Poster 1693. Presented at: American Association for the Study of Liver Diseases: The Liver Meeting Digital Experience; Nov. 13-16, 2020.
Disclosures:
Lawitz reports no relevant financial disclosures.
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