Thyroid News

Adults with chronic hypoparathyroidism treated with recombinant human parathyroid hormone 1-84 for 5 years experienced sustained improvements in mineral homeostasis and modest increases in bone turnover markers, whereas serum calcium remained in the target range with reductions in oral calcium supplements, according to findings from a small, open-label extension study.

Among women positive for thyroid peroxidase antibodies, subclinical hypothyroidism and hypothyroxinemia diagnosed in the first trimester are likely to resolve later in pregnancy; however, subclinical hyperthyroidism is likely to persist, according to findings published in Thyroid.

A cohort of adults with obesity who underwent Roux-en-Y gastric bypass showed markers for poor bone health in the decade after surgery, including elevated bone turnover markers and lower areal bone mineral density, according to findings published in Bone.

The system used to assess malignancy risk in thyroid nodules yields higher malignancy rates in children than in adults, and this may call for new treatment strategies for some types of nodules based on age, according to findings published in Thyroid.

Each month in its cover story, Endocrine Today offers comprehensive reporting on issues of interest to practicing endocrinologists, diabetes educators and other clinicians.

A thyroid cancer risk calculator that takes into account clinical and ultrasonographic variables, including age, sex, nodule size and the presence of cystic fluid, can reliably predict risk for malignancy in most patients, according to findings from a large database analysis.

A genetic predisposition to higher serum parathyroid hormone concentration is not an independent risk factor for developing coronary artery disease, according to findings from a Mendelian randomization analysis.

A significantly higher prevalence of thyroid disorders was found among patients with hidradenitis suppurativa, and additional study to increase the strength of the association was encouraged in a research letter published in Journal of the American Academy of Dermatology.

Roughly one-quarter of adults with features of primary hyperparathyroidism are actually diagnosed with the condition, and this may be part of the reason parathyroidectomy is not performed regularly as a surgical solution, according to findings published in JAMA Internal Medicine.

Horizon Therapeutics has submitted a biologics license application to the FDA for its investigational thyroid eye disease treatment candidate teprotumumab, according to a press release.