Thyroid News

Physiologic variations in thyroid-stimulating hormone concentrations may lead to a misclassification of subclinical thyroid disease for some healthy pregnant women, possibly subjecting women to unnecessary treatment, researchers report.

In May, Healio readers were interested in sex hormones being investigated for treating COVID-19, greater COVID-19 complications for patients with diabetes and obesity, associations between thyroid dysfunction and working hours, and more.

Hypothyroidism was more than 2.5 times more prevalent among Korean adults who worked between 53 and 83 hours per week than those who worked between 36 and 42 hours per week.

A cohort of postmenopausal Japanese women were more likely to sustain a vertebral fracture if they had thyroid-stimulating antibodies compared with women without the antibody, independent of age and severe osteoporosis status, according to findings published in Clinical Endocrinology.

Minor variations in normal-range thyroid function may serve as a novel, modifiable risk factor for stroke, according to findings from a Mendelian randomization analysis published in The Journal of Clinical Endocrinology & Metabolism.

Models projecting incidence of low-risk papillary thyroid cancers suggest there will be more than 200,000 new thyroid cancer diagnoses during the next 5 years, with at least 67,000 of those cases qualifying as candidates for active surveillance due to small tumor size, according to findings published in JAMA Otolaryngology Head & Neck Surgery.

The FDA approved selpercatinib for the treatment of patients with one of three types of tumors that have RET alterations.

A retrospective analysis of diagnosed thyroid cancer cases in California revealed a consistent increase in the diagnosis of larger and more aggressive thyroid tumors that correlated with a rise in incidence-based mortality among men and individuals with tumors larger than 1 cm, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Individuals with cancer and COVID-19 infection appeared at higher risk for severe outcomes than cancer-free individuals with the novel coronavirus, according to results of a multicenter study presented at the virtual American Association for Cancer Research Annual Meeting.

Parathyroidectomies in secondary hyperparathyroidism result in significantly higher costs and higher rates of morbidity, mortality and complications compared to primary hyperparathyroidism, according to a speaker at the virtual National Kidney Foundation Spring Clinical Meetings.