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Pediatric Endocrinology News
Islet autoantibody screening may reveal pediatric type 1 diabetes risk
Presymptomatic type 1 diabetes increases the risk for developing clinical type 1 diabetes in children aged 2 to 5 years, but can be identified via islet autoantibody screening, according to findings published in JAMA.
Impaired autonomic function after exercise observed among healthy teens with type 1 diabetes
A small cohort of healthy adolescents with type 1 diabetes showed signs of altered energy metabolism and cardiovascular autonomic regulation after an exercise test compared with peers of similar age and aerobic fitness level, despite exhibiting normal acute cardiometabolic responses, according to findings from a pilot study published in Pediatric Diabetes.
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Black and Hispanic children underrepresented at diabetes summer camps
During 2018, black and Hispanic children attended diabetes summer camps less frequently than white children, according to findings published in Diabetes Care.
High childhood HbA1c increases premature death risk in type 1 diabetes
Young adults with type 1 diabetes were nearly three times more likely to die before age 30 years if they had poor metabolic control during childhood, according to findings from a Swedish registry-based study.
Early glucocorticoid treatment in congenital adrenal hyperplasia may boost cognitive function
Children and adolescents with congenital adrenal hyperplasia, or CAH, diagnosed early via a neonatal screening program and treated with hydrocortisone had normal psychometric intelligence and executive function compared with population controls, according to findings published in The Journal of Clinical Endocrinology & Metabolism.
Pediatric islet autoimmunity risk rises with BMI gains
Children who have a relative with type 1 diabetes and a single islet autoantibody may be more likely to develop multiple autoantibodies if they have excess weight, according to findings published in Diabetes Care.
Adolescent-specific thyroid reference ranges may avoid misdiagnosis
Reference ranges for thyroid function among adolescents differ substantially from those for adults, according to findings from a longitudinal analysis published in The Journal of Clinical Endocrinology & Metabolism.
Gestational diabetes exposure tied to higher cholesterol, BP in children
Exposure to gestational diabetes in utero is associated with worse cardiovascular health in offspring from childhood through adolescence, according to an analysis of health plan data published in Pediatric Obesity.
Polygenic disease may explain increased bone fragility among children without osteogenesis imperfecta
A cohort of children presenting with increased bone fragility and no extraskeletal signs of osteogenesis imperfecta tended to have a collection of common gene variants that predispose to osteoporotic fracture rather than a monogenic etiology of their condition, according to findings published in the Journal of Bone and Mineral Research.
Blood test may reveal pediatric sleep habits
Differences in the expression level of circulating microRNAs, assessed via a blood test, are positively associated with total sleep duration among healthy, normal-weight children and adolescents, according to findings published in Experimental Physiology.
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