Pediatric Endocrinology News

Children, adolescents and young adults with Down syndrome have higher incidence rates of type 1 and type 2 diabetes compared with matched controls without Down syndrome, according to a study published in Diabetes Care.

Most transgender adolescents who used pubertal blockers and were later prescribed gender-affirming hormone therapy in the Netherlands continued to use hormones as adults, according to data published in The Lancet Child & Adolescent Health.

SAN DIEGO — Infants exposed to gestational diabetes who breastfeed for less than 6 months and drink sugar-sweetened beverages or natural fruit juice are more likely to have obesity during childhood, according to a presenter.

SAN DIEGO — Adolescents with overweight or obesity may have different degrees of weight gain during adulthood based on their obesity phenotype, according to findings presented at ObesityWeek 2022.

SAN DIEGO — Adolescents with obesity had a BMI reduction of 16.1% at 68 weeks with once-weekly subcutaneous semaglutide 2.4 mg plus lifestyle intervention, results similar to those seen with adults, according to top-line results presented at ObesityWeek 2022.

Once-daily liraglutide was not associated with greater weight loss for youths with obesity and Prader-Willi syndrome compared with placebo, according to a study published in The Journal of Clinical Endocrinology & Metabolism.

Most transgender boys reach their predicted adult height after treatment with gonadotropin-releasing hormone analogues and testosterone therapy, according to data published in The Journal of Clinical Endocrinology & Metabolism.

About 30% of a cohort of gender-diverse youths had low whole-body bone mineral density z scores prior to initiation of puberty blockers or gender-affirming hormones, according to findings published in Transgender Health.

Use of continuous glucose monitoring among children and young adults with type 1 diabetes nearly doubled from 2017 to 2020 in the U.S. from 25% to 49% and was associated with lower HbA1c for users vs. non-users, according to registry data.

Adolescent girls with type 1 diabetes lost trabecular volumetric bone mineral density over 1 year compared with gains for girls without diabetes, with greater loss at higher HbA1c levels, according to a speaker.