Neuroendocrinology News

Men with hypersexual disorder have higher levels of oxytocin compared with men without the disorder, and behavioral therapy to resolve hypersexual disorder was linked to reductions in oxytocin, according to study data.

Nearly all responders to a 26-week course of oral octreotide maintained a biochemical response and symptomatic control of acromegaly at 62 weeks, according to data from the MPOWERED trial.

One-third of acromegaly and growth hormone deficiency studies report discrepancies between patient-reported outcomes and biochemical outcomes, with many using unvalidated and poorly reported outcome measures, data from a meta-analysis show.

Electronic health records data from a European cohort suggest endocrine secondary effects after pediatric brain tumor treatment develop within 2 years of diagnosis, including pituitary deficiencies, hypothyroidism and obesity.

The FDA approved the steroidogenesis inhibitor levoketoconazole for adults with Cushing’s syndrome for whom surgery is not an option or has not been curative, according to an industry press release.

People with metastatic pheochromocytomas and paragangliomas should be closely monitored and undergo routine cross-sectional imaging while also being evaluated by a multidisciplinary team, according to a guideline published in Pancreas.

An updated guideline for the treatment of Cushing’s disease focuses on new therapeutic options and an algorithm for screening and diagnosis, along with best practices for managing disease recurrence.

Patients with neuroendocrine tumors are at greater risk for cancer-associated death compared with death due to other causes; however, mortality rates vary according to tumor site.

Dentists and orthodontists are uniquely positioned to identify the early facial manifestations of acromegaly, though new survey data suggest more awareness of the condition is needed to improve early diagnoses.

The FDA approved the first once-weekly formulation of somatropin for children with growth hormone deficiency, according to an industry press release.