Neuroendocrinology News

The Endocrine Society released its first-ever clinical guidelines for the diagnosis and treatment of patients with hyperprolactinemia.

Everolimus was linked to progression-free survival more than twice as long as placebo in a cohort of patients with pancreatic neuroendocrine tumors, according to study results.

Four Irish families with histories of acromegalic gigantism may share more than a condition with the famous 18th-century Irish giant Charles Byrne: They may have a common ancestor as well.

A 37-year-old man was referred for the evaluation of an abnormal pituitary MRI scan with a question of the appropriate interval of time to repeat his pituitary imaging. When he was 20 years old, he developed rapid onset of nausea, vomiting and headache 2 to 3 days after a complicated wisdom tooth extraction. He had a CT scan at that time that, by his report, was unremarkable.

A 65-year-old woman with a history of type 2 diabetes, coronary artery disease with congestive heart failure and nephropathy presented with severe, intermittent, crampy abdominal pain and chronic constipation alternating with diarrhea. She complained of a long history of subjective flushing, but denied wheezing and palpitations. She was felt to have a possible bowel obstruction, and an abdominal CT scan was performed that showed a mass near the terminal ileum.

Pasireotide was effective at reducing the cortisol levels and improving associated signs and symptoms in patients with Cushing’s disease, according to data from a phase 3 trial that were presented at the 14th Congress of the European Neuroendocrine Association.

The Endocrine Society 92nd Annual Meeting

New data demonstrate that vitamin D deficiency is closely associated with the chronic fatigue that often follows post-traumatic brain injury.

A consensus group has reviewed the criteria for cure of acromegaly, and updated guidelines detailing the latest management criteria were published in the Journal of Clinical Endocrinology & Metabolism.

This 46-year-old man was diagnosed with secondary hypothyroidism in the setting of panhypopituitarism and an empty sella. In a second case challenge, we identified an elevated serum testosterone level from a compromised blood draw. He is now returning for follow-up and is presenting the next challenge.