Hormone Therapy News

In girls with Turner syndrome, a younger age at estrogen therapy initiation is associated with a longer time to menarche, whereas presence of a mosaic karyotype is associated with a shorter time to menarche, according to published findings.

Postmenopausal women who reported bothersome hot flashes experienced a similar reduction in symptoms when assigned to antidepressant therapy or hypnosis, whereas a combination of the two therapies yielded no greater benefit than the individual treatments, according to findings from a pilot, proof-of-concept study.

Previous estrogen exposure in women with multiple endocrine neoplasia type 1 may affect size of pancreatic neuroendocrine tumors, but exposure is not correlated with time to pancreatic neuroendocrine tumor diagnosis, according to published findings.

Oral dydrogesterone provided safety and efficacy similar to that of micronized vaginal progesterone for luteal phase support in women undergoing in vitro fertilization, published findings show.

In healthy men with obesity and low levels of total testosterone, testosterone therapy reduced levels of leptin beyond the effects of diet alone, according to findings from Australia.

Postmenopausal women receiving estrogen therapy for osteoporosis or osteopenia were less likely to have severe periodontitis compared with treatment-naive women, according to findings published in Menopause.

Men with hypogonadism using a topical testosterone replacement gel therapy administered with a hands-free cap applicator reported high satisfaction with the treatment and had improved testosterone levels, according to published data.

One year of testosterone treatment did not improve memory or other cognitive functions compared with placebo among older men with low testosterone and age-associated memory impairment, according to study findings published in JAMA.

Prepubertal and adolescent children with Prader-Willi syndrome treated with recombinant human growth hormone therapy before the onset of puberty saw increased linear growth and adult height over at least 3 years of treatment, according to a worldwide, retrospective cohort study.

The risk for adverse cardiovascular outcomes, including stroke and acute myocardial infarction, may be decreased with the use of testosterone replacement therapy in men with androgen deficiency, according to recent findings.