Hormone Therapy News

In children treated with growth hormone, those with a prior malignancy or an underlying serious medical condition unassociated with growth hormone deficiency had higher mortality rates than those with idiopathic growth hormone deficiency or other growth disorders, published findings indicate.

After cessation of a weight-loss program combined with testosterone therapy, men with obesity did not retain favorable changes in body composition, according to findings published in Clinical Endocrinology.

In postmenopausal women, the use of oral hormone therapy is associated with a higher risk for hearing loss, with risk increasing with a longer duration of use, according to findings published in Menopause.

In women with polycystic ovary syndrome, the use of any oral contraceptive was associated with a rise in triglyceride and total cholesterol levels over time, and oral contraceptives containing third-generation progestins did not offer substantial advantages, according to findings from a systematic review and meta-analysis.

The U.S. Preventive Services Task Force has issued a draft recommendation against the use of combined estrogen and progestin for the prevention of chronic conditions in postmenopausal women, as well as the use of estrogen for the prevention of chronic conditions in postmenopausal women who had a hysterectomy.

TherapeuticsMD recently received a Complete Response Letter from the FDA in reply to its New Drug Application for TX-004HR, an investigational applicator-free estradiol vaginal softgel capsule for the treatment of moderate to severe vaginal pain during sexual intercourse, according to a company press release.

AUSTIN, Texas — Testosterone replacement therapy may lower the risk for myocardial infarction, stroke and all-cause mortality in men with secondary hypogonadism.

AUSTIN, Texas — Contrary to public perception, most androgen abusers are not elite athletes seeking to enhance performance, but instead are nonathletes pursuing a leaner and more muscular appearance, according to a speaker at the American Association of Clinical Endocrinologists Annual Scientific and Clinical Congress.

Women with functional hypothalamic amenorrhea do not have significantly improved bone health with the use of hormonal therapy vs. placebo and calcium supplements, according to findings published in the Journal of the Endocrine Society.

Women assigned combined hormonal contraceptives who experience a venous thromboembolism may have vascular contraindications suggesting inappropriate prescriptions, according to findings published in the Journal of the Endocrine Society.