Hormone Therapy News

There may be mortality, musculoskeletal and cardiovascular benefits from testosterone therapy among men with low testosterone due to opioid use, according to findings published in JAMA Network Open.

SAN ANTONIO — Two common hormone therapy regimens had opposite long-term effects on breast cancer incidence among postmenopausal women, according to results from two large randomized controlled Women’s Health Initiative trials presented at San Antonio Breast Cancer Symposium.

An analysis of medical records from a large German endocrine clinic suggests more transgender men are seeking gender-affirming treatment, with nearly all individuals reporting an improvement in their overall situation after initiating hormone therapy, according to findings published in Clinical Endocrinology.

PHILADELPHIA — Transgender and gender-nonconforming adults who experience discrimination are more likely to report increased CV risk factors, such as excessive drinking and short sleep, but social support from family members may weaken the association.

The prevalence of type 1 diabetes among transgender and gender-nonconforming youths is more than nine times higher than that of the general population, with researchers exploring the role of increased psychological stress among adolescents with both diagnoses, according to findings from a single-center study published in Pediatric Diabetes.

Chinese girls diagnosed with central precocious puberty achieved greater gains in total height when treated with combination gonadotropin-releasing hormone analogues, or GnRHa, plus recombinant growth hormone therapy, or rhGH, with low predicted adult height and greater bone age predicting greater success with treatment, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

After undergoing 1 year of gender-affirming hormone therapy, transgender men appear to experience increased insulin sensitivity whereas insulin sensitivity tends to decrease for transgender women, according to findings published in Diabetes Care.

Trunk fat mass and whole-body fat mass decreased with testosterone therapy among men with borderline low testosterone levels following treatment for cancer, according to findings published in PLOS Medicine.

The FDA has issued a complete response letter regarding a new drug application for an oral formulation of testosterone undecanoate, according to a press release from Lipocine.

A Texas court case involving a custody dispute over a young child who may identify as transgender has ignited a national debate about the appropriate course of pediatric treatment, with the state’s governor calling for an investigation into the case and one legislator proposing a bill that would prohibit the use of pubertal blockers for minors.